07/2019. I've read that pseudoephedrine is psychoactive in various books and I know it is the major alkaloid of Sida cordifolia. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Pseudoephedrine is in a class of medications called nasal decongestants. Continue 1. I am also ADHD and studying for Step 2 CK. Pseudoephedrine has weak agonist activity at beta-adrenergic receptors. FREE Shipping on orders over $25 shipped by Amazon. Pseudo and nor pseudo are found in many OTC products such as flu medication, and a few extra steps are generally required to draw the precursor out of the medication prior to Cat production. The most common indication for pseudoephedrine is as a decongestant, for conditions including nasal congestion, sinus congestion, and eustachian tube congestion, as it shrinks swollen nasal mucous membranes and reduces tissue hyperemia and edema. Nasal congestion is caused when blood vessels in the cavities in your nose (sinuses) become swollen. Pseudoephedrine is phenethylamine that is an isomer of Ephedrine with the sympathomimetic property. Pseudoephedrine is used to relieve nasal congestion caused by colds, allergies, and hay fever. Reputation Points: 10. I wouldn't call it recreational but ephedrine and pseudoephedrine are ok study aids. Good Sense Maximum Strength Nasal Decongestant PE, Phenylephrine HCl, 10 mg tablets, 72 Count. Note: some tablets may not fully dissolve and the tablet shell may be visible in the stool. Call your doctor if your symptoms have not improved within seven days of treatment, or if you develop a fast, pounding or uneven heartbeat, severe dizziness or anxiety, severe headache, an allergic-type reaction, fever or rash. See more. First manufactured in the United States in 1928, the drug Methcathinone was used in the Soviet Union as an anti-depressant in the 1930s and '40s. Pseudoephedrine. It can be used for up to seven days in a row and comes in a generic form. Here in the Netherlands, herbal E's with pseudoephedrine in it, have been sold without any health problem, for a decade. Whilst it is a schedule 7 drug in SA, it is readily available on the black market, and very often the suppliers are Chinese, as the bulk of the world's ephedrine is manufactured there. The quantity that can be purchased is also limited. Always talk with a doctor before giving cough or cold medicines to children. Pseudoephedrine belongs to the class of medicines known as nasal decongestants. This is no longer the case. 2. 6. $4.22 $ 4. Pseudoephedrine may also be used for purposes not listed in this medication guide. I have a bad cold and had to get the "real" Sudafed to help with my sinuses and my symptoms. Pseudoephedrine and ephedrine are medicines used as nasal decongestants. Studies in the USA indicate that restricting the sale of pseudoephedrine to the public as a medicine has had little impact on the morbidity and number of arrests associated with methamphetamine abuse. This site uses cookies. Pseudoephedrine is still available OTC in Michigan, but you have to be 18 and are only allowed to purchase 2 packages not to exceed 48 tablets. It is relatively easy to make, and quick as well. The same typical therapeutic dose of pseudoephedrine (60 mg) produced a urinary concentration of more than 5 microg/mL for cathine and of more than 100 microg/mL for pseudoephedrine in 2 of 9 subjects only. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Long-term methamphetamine abuse can cause addiction, anxiety, insomnia, mood disturbances and violent behavior. As the pressure for students to perform increases, they're turning illegal drugs for a boost. To give you an idea, it is very possible for people to buy Cat at 4pm that was manufactured that morning. Do not use pseudoephedrine if you are pregnant or breastfeeding unless under a doctor's advice. 4.6 out of 5 stars 5,127. What effects do the drug have on the user? Let it also be known simply for further depth, that I was a fairly avid partier in high school, with drinking and herb smoking as my primary staple-goods. Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. Picture: Thomas Holder/EWN, City Power: Move to 2-hour load shedding schedule was to align with Eskom. In the pseudoephedrine group, pseudoephedrine sulfate 120 mg BID was used with plasma peak concentration at 7.22 h and half-life of 6.48 h. Desloratadine 5 mg QD with a plasma peak concentration at 3.98 h and half-life of 26.8 h was used in the antihistamine group. He's a former Cat user himself. 3. Avoid taking pseudoephedrine if you also take caffeine supplements, diet pills or other stimulants (such as ADHD medications). Both pseudoephedrine and phenylephrine have a good safety record, but the efficacy of pseudoephedrine as a nasal decongestant is supported by clinical trials. I don't think there is a massive export market for it, as the domestic market is very hungry and supply often cannot meet demand. Long-term users report broken teeth from grinding their jaws too much, extreme weight loss, complete loss of libido (impotency), sores on the skin, and loss of bone density and muscle strength. However, Pseudoephedrine only provides symptom relief, it does not cure a cold. Available for Android and iOS devices. Important information. Shake the oral suspension well before measuring out the correct dose. Medicines that interact with pseudoephedrine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with pseudoephedrine. There has been increasing concern that these active substances can be … This study investigates its possible ergogenic effect through a systematic review. The problem is that it causes people to hyper focus, which is bad. Pseudoephedrine is a decongestant that relieves a stuffy or blocked nose (nasal congestion). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use pseudoephedrine only for the indication prescribed. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. What is the primary demographic using the drug currently and historically? Methods: The study was a double-blind, randomized, parallel-group, placebo-controlled trial conducted over three study days at a single center. Pseudoephedrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion. About pseudoephedrine. It used to be the middle to upper class white people in the 18 - 35 age group. The amount of pseudoephedrine that an individual can purchase each month is limited and individuals are required to present photo identification to purchase products containing pseudoephedrine. We comply with the HONcode standard for trustworthy health information -, https://www.drugs.com/ppa/pseudoephedrine.html, Pseudoephedrine Extended-Release Tablets (12 Hour), Pseudoephedrine Extended-Release Tablets (24 Hour). Consumer Reports explains why using ADHD meds like Adderall as study drugs is a bad idea. Individuals purchasing pseudoephedrine must produce photo ID and supply personal information that the store must keep for at least two years. Pseudoephedrine must never be given to children under the age of four. This can happen when you have: a cold. Subjectively, I'd put eph + caffiene on about the same level as a 3-5mg dose of addy. It works by causing narrowing of the blood vessels in the nasal passages. We have noted (anecdotally, with more research needed) that there is a correlation between porn addiction and Cat use. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Pseudoephedrine treatment is thought to date back thousands of years, and Ephedra sinica — a Himalayan shrub from which ephedrine and its stereoisomer, pseudoephedrine, are derived — was recommended for use in colds, fever and asthma in an early Chinese pharmacopoeia.4 Successful chemical synthesis of pseudoephedrine was reported in the 1920s, although modern commercial production is by yeast fermentation of dextrose in the presence of benzaldehyde. It causes vasoconstriction by … Photo ID must be produced to purchase it and pharmacies must keep records relating to the purchase for at least two years. Methods: The study was a double-blind, randomized, parallelgroup, placebo-controlled trial conducted over three study days at a single center. Pseudoephedrine and ephedrine are important P medicines which are used as decongestants. You should refer to the prescribing information for pseudoephedrine for a complete list of interactions. I ruptured my Achilles tendon completely walking down stairs 5 years after stopping. Amazon's Choice for pseudoephedrine. I am not a position to use DNMs (parents house). Significantly more effective as a decongestant than phenylephrine. … It is also used to temporarily relieve sinus congestion and pressure. A friend of mine took some pseudoephedrine tabs and got stimulating effects. An RCT comparing the efficacy and safety of cetirizine (5 mg), pseudoephedrine (120 mg bid), and their combination found that insomnia was the most common complaint in patients taking pseudoephedrine (Bertrand et al., 1996). I used caffeine pills last year and they helped tremendously.. until my tolerance reached the point where 600+mg wasn't helping. Pseudoephedrine comes in tablet forms, including an extended-release tablet which allows for taking fewer doses. Speak to your doctor about how drug interactions should be managed. Owing to its similar composition to ephedrine and other amphetamines, pseudoephedrine mirrors some of its ergogenic effects. Pseudoephedrine is an orally active sympathomimetic amine exerting its decongestant action by acting directly on α-adrenergic receptors in the respiratory tract mucosa producing vasoconstriction resulting in shrinkage of swollen nasal mucous membranes, reduction of tissue hyperemia, edema, and nasal congestion, and an increase in nasal airway patency. Do not give pseudoephedrine to children without talking to a doctor first. Long-term users will also often snap tendons or tear muscles doing normal things. Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Cat's popularity has exploded in the last 2-3 years, nearly doubling every year. Herbal XTC's with good Sida extracts I found to be thebest. Pseudoephedrine. One may be the school teacher who was using upwards of 10 grams a day before stopping. Will cause a false-positive result on a urine test for amphetamines. Otherwise known as Cat or Jeff, the effects are similar to Methamphetamine (Meth) but it is made by oxidizing the pseudoephedrine, rather than reducing it. Gerard Newbie. Pseudoephedrine displaces norepinephrine from its storage sites and released norepinephrine acts as the alpha agonist. I am a college student with a very limited attention span. Snorted, smoked, or injected, the user feels a sudden euphoria and an increase in alertness as their hearts race and they begin to "rush". Talk to your doctor or pharmacist before using any other cold or flu remedies as they may also contain pseudoephedrine or another decongestant. Tablets, chewable tablets, liquid and nasal preparations of pseudoephedrine effectively treat nasal and sinus congestion; however, the sale of cold and flu products containing pseudoephedrine is limited to behind the counter because pseudoephedrine may be used for the illicit production of methamphetamine. Do not give pseudoephedrine to a child younger than 4 years old. What are some of the most interesting case studies you have seen? Copyright 1996-2021 Drugs.com. Revision date: March 23, 2020. antidepressants, such as amitriptyline, amoxapine, clomipramine, doxepin, imipramine, isocarboxazid, or phenelzine, diabetes medications, such as metformin, glimepiride, glipizide, glyburide, or insulin, heart medications, such as atenolol, betaxolol, bisoprolol, carvedilol, migraine medications, such as dihydroergotamine or ergotamine. Pseudoephedrine has two asymmetric carbon atoms. Last updated on March 23, 2020. If you have any questions, ask your doctor or pharmacist. the flu. Other manufacturers will use pseudo- or nor pseudo-ephedrine in the manufacture of the product. - Anonymous user. Is the drug manufactured locally and is it imported or exported? The precursor to the production of Cat - ephedrine - is imported. 4. Speed-balling & pseudoephedrine: Youth using drugs for study. Advice on using Pseudoephedrine as a study aid. Learn vocabulary, terms, and more with flashcards, games, and other study tools. At a university in Johannesburg, some students have been experimenting with this scheduled drug for a variety of reasons. Sleeplessness is a common side effect. Pseudoephedrine is a decongestant that constricts (shrinks) dilated blood vessels within the nose, relieving congestion.